Pediatrics, Formulation Development
A Randomized Pilot Study to Evaluate the Stability, Taste, and Palatability of a Novel Liquid Formulation of Tenapanor
2 January 2025 Read MoreDownload our articles & publications
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Pediatrics, Formulation Development
A Randomized Pilot Study to Evaluate the Stability, Taste, and Palatability of a Novel Liquid Formulation of Tenapanor
2 January 2025
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Translational Pharmaceutics, Clinical Pharmacology, Spray Drying
Placebo-controlled First-in-Human Study of Oral TQS-168 in Healthy Volunteers
17 December 2024
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Clinical Pharmacology
In Vitro and Clinical Evaluations of UGT1A1-, P-gp-, OATP1B1-, and BCRP-Mediated Drug–Drug Interactions of Belumosudil, a Potent ROCK2 Inhibitor
17 December 2024
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First-in-Human, Clinical Pharmacology
First-in-human safety, tolerability, pharmacokinetics and pilot food-effect study of the candidate antimalarial compound MMV367
12 March 2024
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Clinical Pharmacology, Formulation Development, Pediatrics
Two-Part Phase 1 Study to Evaluate the Taste Profile of Novel Belumosudil Oral Suspensions, Relative Bioavailability, and Food Effect
12 February 2024
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Pharmacokinetics , Pharmacodynamics
Pharmacokinetics, Pharmacodynamics and Bioavailability of ACM-001.1 (S-Pindolol Benzoate) in Healthy Volunteers
13 December 2023
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Clinical Pharmacology, Human ADME
Astrazeneca - A Phase 1 Study to Evaluate Absolute Bioavailability and Absorption, Distribution, Metabolism and Excretion of Savolitinib in Healthy Male Volunteers
6 June 2023
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Formulation Development, Human ADME, First-in-Human
Astrazeneca - Mass balance recovery and disposition of AZD4831 in humans
13 January 2023
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Pediatrics, Drug Product
Practical and operational considerations related to pediatric oral drug formulation: An industry survey
14 December 2022
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Materials Science
Controlled synthesis of SPION@SiO2 nanoparticles using design of experiments
13 December 2022
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Clinical Pharmacology
CC-99677: A Novel, Oral, Selective Covalent MK2 Inhibitor, Sustainably Reduces Pro-inflammatory Cytokine Production
23 August 2022
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Clinical Pharmacology
CC-99677, A Novel, Oral, Selective Covalent MK2 Inhibitor, Sustainably Reduces Pro-inflammatory Cytokine Production
23 August 2022
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Human ADME
ADME of opicapone in human healthy volunteers
16 June 2022
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Translational Pharmaceutics, Clinical Pharmacology, First-in-Human
Safety, tolerability and pharmacokinetics of the oligomer modulator anle138b with exposure levels sufficient for therapeutic efficacy in a murine Parkinson model: A randomised, double-blind, placebo-controlled phase 1a trial
3 May 2022
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Drug Product Optimization
A Phase 1 Pharmacokinetic Drug Interaction Study of Belumosudil Coadministered With CYP3A4 Inhibitors and Inducers and Proton Pump Inhibitors
15 March 2022
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Drug Product Optimization
Absolute Bioavailability, Mass Balance, and Metabolic Profiling Assessment of [14C]-Belumosudil in Healthy Men: A Phase 1, Open-Label, 2-Part Study
15 March 2022
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Drug Product Optimization
ACCP: A Phase 1 Pharmacokinetic Drug Interaction Study of Belumosudil Coadministered With CYP3A4 Inhibitors and Inducers and Proton Pump Inhibitors
7 March 2022
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Human ADME, Clinical Pharmacology, First-in-Human
Astrazeneca - Characterization of Clinical ADME & Pharmacokinetics of Velsecorat Using an IV Microtracer Combined with an Inhaled Dose in Healthy Subjects
2 February 2022
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Modified Release, Formulation Development
Development of a Once‑Daily Modified‑Release Formulation for the Short Half‑Life RIPK1 Inhibitor GSK2982772 using DiffCORE Technology
10 January 2022
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Clinical Pharmacology
Effect of Miricorilant, a Selective Glucocorticoid Receptor Modulator, on Olanzapine-Associated Weight Gain in Healthy Subjects
3 January 2022
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Clinical Pharmacology, First-in-Human
Dose Finding and Food Effect Studies of a Novel Abiraterone Acetate Formulation for Oral Suspension in Comparison to a Reference Formulation in Healthy Male Subjects
16 December 2021
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Human ADME, First-in-Human
Scientific Paper_Pharmacokinetics and Metabolism of Ziritaxestat (GLPG1690) in Healthy Male Volunteers Following Intravenous and Oral Administration
1 September 2021
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Bioanalysis
Scientific Paper_Inductively coupled plasma mass spectrometry method for plasma and intracellular antimony quantification applied to pharmacokinetics of meglumine antimoniate
1 May 2021
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Formulation Development, Oral Peptides
Development and approval of rybelsus (oral semaglutide): ushering in a new era in peptide delivery
1 May 2021
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Modified Release
Scientific Paper_ Development of a Prototype, Once-Daily, Modified Release Formulation for the Short Half-Life RIPK1 Inhibitor GSK2982772
1 February 2021
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Clinical Pharmacology
A phase 1/1b study of PUR1900, an inhaled formulation of itraconazole, in healthy volunteers and asthmatics to study safety, tolerability and pharmacokinetics
23 January 2020
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Clinical Pharmacology
2019 Jones et al - Absence of pharmacokinetic interactions between the Bruton's Tyrosine Kinase Inhibitor Fenebrutinib and Methotrexate ~Gen
21 January 2020
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Translational Pharmaceutics, Formulation Development, Clinical Pharmacology
Application of a Novel ‘Make and Test in Parallel’ Strategy to Investigate the Effect of Formulation on the Pharmacokinetics of GDC-0810 in Healthy Subjects
23 November 2018
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Clinical Pharmacology
Relationship Between Oral Semaglutide Tablet Erosion and Pharmacokinetics: A Pharmacoscintigraphic Study
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